Plasmodium vivax and plasmodium knowlesi duffy receptor
Type
Sample
DNA segments encoding the Duffy receptor of a Plasmodium parasite A useful protein in the development of a potential malaria vaccine has been developed by cloning the gene for the Duffy binding receptor of Plasmodium vivax, a human malaria. Duffy blood group determinants on human erythrocytes are known to be essential for invasion by both the P. vivax and P. knowlesi malaria strains. A candidate malaria vaccine could result from the use of antibodies to the recombinant Duffy receptor binding protein or the receptor protein itself functioning through competitive blocking therapy.
Condition of use
n/a
IP information
Granted Patent Reference Number(s): US 5541292
Abandoned Patent Reference Number(s): US 5198347