Identification of a Region of Merozoite Surface Protein 1 (MSP-1) Necessary for Protective Immunity

Type
Technology/Assay

The invention pertains to full-length polypeptides and fragments from naturally occurring Merozoite Surface Protein 1 (MSP-1; a protein expressed in later stage erythrocytic malaria) including vectors having encoding nucleic acids thereof that are useful as DNA vaccines. The intent was that the MSP-1 proteins expressed through these vectors would generate protective immune responses against subsequent infection by Plasmodium falciparum, the pathogen responsible for malaria.

Disease
Malaria
Research areas
Basic research
Vaccine
Condition of use

n/a

IP information

Abandoned Patent Reference Number(s): US 60/503,076