Optimisation of fenarimol series for the treatment of Chagas disease (2nd release of data). DNDi data is made available herewith freely to third parties. Use of these data anywhere in the world is therefore not subject to any licensing terms.
Fenarimol as starting point for SAR investigations aimed at improving activity against T.cruzi and developing compounds suitable for in vivo characterisation. This second release of data contains data sets on the two more advanced fenarimol series, from which two preclinical candidates were identified.