Share of phosphodiesterase (PDE) V inhibitors and calcium channel blockers to screen the compounds for activity against intracellular M. tuberculosis

Status
On going
Start date
Start stage
Screening
Disease
Tuberculosis
Research areas
Basic research
Drug

Eisai will provide IDRI investigators with selected phosphodiesterase (PDE) V inhibitors and calcium channel blockers. The investigators will use IDRI's high-content imaging system to screen the compounds for activity against intracellular M. tuberculosis to identify candidates for further drug development.