Screening of Open Global Health Library for Schistosomiasis Drug Discovery

Status
On going
Start date
Start stage
Discovery

Schistosomiasis affects hundreds of millions of people worldwide, mostly in the world’s poorest countries. Praziquantel (PZQ) is the only medication currently used in mass drug administration programs, raising the risk of drug resistance. There is a critical need to develop new therapeutics that target essential pathways that are not affected by PZQ. Dr. Emmanuel Oluwadare Balogun at Ahmadu Bello University will screen the Open Global Health
Library of Merck KGaA, Darmstadt, Germany to identify antischistosomal compounds with novel mechanisms of action.