Screening of Merck KGaA, Darmstadt, Germany’s Mini Library for Chagas Disease, Human African Trypanosomiasis, and Leishmaniasis Drug Discovery

Status
On going
Start date
Start stage
Screening
Disease
Chagas disease
Leishmaniasis
Human African trypanosomiasis (HAT)
Research areas
Drug

Chagas disease, human African trypanosomiasis, and leishmaniasis are neglected tropical diseases that collectively affect millions of people worldwide. Improved treatments for all three diseases are greatly needed. Merck KGaA, Darmstadt, Germany will provide GRIDD investigator Dr. Vicky Avery with its Mini Library to screen for Chagas disease, human African trypanosomiasis, and leishmaniasis drug discovery.

Merck KGaA, Darmstadt, Germany’s Mini Library is a collection of drug-like former Biopharma research and development compounds and their derivatives. The compounds cover a wide range of molecular targets, including enzymes, hormone and neurotransmitter receptors, transporters, and ion channels.