Highly potent Hsp90 inhibitors to screen against Onchocerca worms

Status
On going
Start date
Start stage
Screening
End stage
Hit ID

Merck KGaA, Darmstadt, Germany will provide a University of Buea researcher with a subset of highly potent Hsp90 inhibitors to screen against Onchocerca worms, and identify compounds that selectively kill both microfilariae and adult O. volvulus, without adverse effects to Loa loa microfilariae.