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The University of Papua New Guinea, School of Medicine and Health Sciences, is a medical and health services...
Developing World Health is a not for profit charitable company, working on providing a comprehensive...
Ahmadu Bello University, established in 1962, is a federal university in Zaria, Nigeria whose mission is to...
This fellowship of Indra Wibowo from the Institut Teknologi Bandung, Indonesia, with Wai-Hong Tham from the Walter and Eliza Hall Institute of Medical Research (WEHI), Australia, aimed to identify functional blocking antibodies that inhibit red blood cell binding and ligand-receptor interactions present in individuals in a region of high Malaria transmission in Indonesia. PfRh5 is one of the leading vaccine candidates against blood stage P. falciparum and PfRh4 governs the major invasion pathway independent of glycophorin-mediated entry.
Institute Pasteur Madagascar (IPM) is working with cohorts of EPTB (Extrapulmonary tuberculosis) patients in collaboration with local clinicians to better diagnose EPTB and accelerate diagnosis. IPM is gathering clinical, bacteriological as well immunological data and samples from these patients (clinical extrapulamonary Mtb (mycobacterium tuberculosis) strains, blood samples and other fluids), aiming to increase the Institute immunological investigation capacities in order to propose new options with new tools to diagnose EPTB with an integrated approach (host, pathogen, immune response). At IPM, the human host capacities need to be upgraded to meet with the international standards and increase the capacity to understand the host-pathogen interaction and build tools to fight against EPTB from this interaction. In this project, Paulo Ranaivomanana from IPM and Anna Coussens from WEHI work together to strengthen IPM capacities in assessing the immunological correlates that may be associated with extrapulmonary dissemination of Mtb. Understanding the determinants of Mtb dissemination can be useful to build diagnostic tools for EPTB.